Shoulder pain after recent stroke (SPARS): hemiplegic shoulder pain incidence within 72 hours post-stroke and 8-10 week follow-up (NCT 02574000)

Abstract

Objectives

This study aimed to identify very early incidence of hemiplegic shoulder pain within 72 hours (HSP), how clinical assessment was related to pain at 8–10 week follow-up and explore current standard therapy/management.

Design

Observational, prospective.

Setting

Teaching hospital hyper-acute and follow-up stroke services.

Participants

121 consecutive patients with confirmed cerebral infarct/haemorrhage recruited within 72 hours of stroke onset.

Interventions

N/A.

Main outcome measures

Subjective report of pain severity and aggravating factors: using numerical rating scales and pain questionnaire (ShoulderQ), shoulder abductor and flexor muscle strength (Oxford MRC Scale), Neer’s Test of sub-acromial pain, shoulder subluxation and soft tissue shoulder palpation.

Results

At initial assessment (<72 hours), 35% (42/121) reported HSP. At follow-up (8–10 weeks), 44% (53/121) had pain: pain persisted in 32 of the original 42, resolved in 10 and had developed since initial assessment in 21. Pain at follow-up was associated with a statistically significant higher frequency of severe shoulder muscle weakness (MRC grade ≤2) and gleno-humeral subluxation at initial assessment. Soft tissue palpation and Neer’s Test detected pain but did not predict development of HSP. 50/121 patients had 140 therapy interventions, particularly targeted to those with a higher HSP risk.

Conclusion

This study reports HSP at an earlier time point after stroke than previous publications. Patients with severe arm weakness and/or shoulder subluxation within 72 hours are at significantly higher risk of HSP at 8–10 weeks. These data highlight the high incidence of HSP, the non-standardized therapy approach, and can inform sample size calculations for future intervention studies.

Clinical Trial Registration: NCT02574000 (clinicaltrials.gov).

Citation

Shoulder pain after recent stroke (SPARS): hemiplegic shoulder pain incidence within 72 hours post-stroke and 8–10 week follow-up (NCT 02574000)